Informatics, its artefacts and methods, change(d) our society and world, from the individual personal level up to the current geo-political powerplay. Today, Information Technology (IT) serves as the operating system of our society. However, digital technologies have a double face: besides keeping our society running they can contribute to solving major problems of humanity, but at the same time they have also acquired the dubious reputation of being unethical and promoting socially undesirable power relations. AI is a good example of this tricky situation – one could almost call it a Faustian bargain. “Our” technologies are disrupting societies and questioning our understanding of what it means to be human. However, this development is not God-given; alternative paths are possible, for people and society. “Digital Humanism” is such an approach to develop digital technologies centered on human and societal needs, building on and furthering social achievements. We plan a keynote as introduction, where we discuss this approach, the international initiative behind it as well as its achievements and related challenges. For the following panel, we will focus on the global perspectives and could suggest relevant international experts in the area of Digital Humanism. We would very much welcome on the panel, experts from China, Asia and the Global South in order to discuss and elaborate on the potential of the Digital Humanism Initiative in this part of the world and for the Global Digital Compact.